Engineered in-vitro cell line mixtures and robust evaluation of computational methods for clonal decomposition and longitudinal dynamics in cancer.
Genomic consequences of aberrant DNA repair mechanisms stratify ovarian cancer histotypes.
Genetic profiling of MYC and BCL2 in diffuse large B-cell lymphoma determines cell-of-origin-specific clinical impact.
CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours.
Robust high-performance nanoliter-volume single-cell multiple displacement amplification on planar substrates.
Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer.
The clonal and mutational evolution spectrum of primary triple-negative breast cancers.